INTRAMUSCULAR PHENYLEPHRINE DOSE COMPARISON FOR PREVENTION OF SPINAL ANESTHESIA INDUCED HYPOTENSION DURING CESAREAN SECTION: A PROSPECTIVE RANDOMIZED DOUBLE BLIND STUDY

OBJECTIVE: to determine the more effective dose of intramuscular (IM) Phenylephrine in preventing hypotension due spinal anesthesia (SA) administered for cesarean section. METHODS: The study was conducted from January1, 2020 July 31, 2020, at Rehman Medical Institute, Peshawar, Pakistan. Sixty participants American Society Anesthesiologists (ASA) physical status 1 and 2, scheduled elective section (CS) under SA were enrolled this prospective double-blind randomized into two equal groups, P4-group P8-group. received IM 04 mg P8-group 08 before SA. incidence intensity hypotension, rescue doses any adverse event, recorded. Data collected analyzed using Epi lnfo ™ version 7.2.5. RESULTS: Mean age patients P4-Group P8-Group 28.10±4.39 years 28.33±4.95 respectively. There no statistically significant differences groups with respect demographic clinical characteristics. Hypotension occurred 33.3% (n=20/60) participants. 46.7% (n=14/30) 20% (n=6/30) In P8-group, risk 1.5 times less common compared 95% confidence interval 1.02–2.19 (p=0.02). also difference between onset groups. Those who developed had consumed a lesser amount (p-value <0.01). CONCLUSION: preemptively controls induced sustained way fit